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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD7
All Species:
6.97
Human Site:
S558
Identified Species:
15.33
UniProt:
Q6ZUT3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZUT3
NP_919253.1
714
81614
S558
Q
E
A
I
A
R
T
S
G
R
S
N
I
N
V
Chimpanzee
Pan troglodytes
XP_001142428
1045
118548
T596
E
P
L
H
K
F
H
T
N
F
L
K
E
I
E
Rhesus Macaque
Macaca mulatta
XP_001095803
714
81414
S558
Q
E
A
I
A
G
T
S
V
R
S
N
I
N
V
Dog
Lupus familis
XP_549262
787
88688
N635
A
R
T
T
G
R
S
N
I
N
V
D
L
E
V
Cat
Felis silvestris
Mouse
Mus musculus
A2AD83
703
80312
E558
N
I
N
V
E
P
E
E
E
D
P
H
L
D
D
Rat
Rattus norvegicus
Q9WTP0
879
98224
L655
S
D
S
E
T
E
G
L
V
F
A
R
D
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506249
1047
119790
H596
F
E
P
L
H
K
F
H
T
N
F
L
K
E
I
Chicken
Gallus gallus
XP_426268
693
77887
E546
A
G
T
S
V
G
P
E
G
E
R
R
Q
G
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
S475
S
R
S
R
G
N
T
S
S
G
S
E
S
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
S678
G
R
D
V
S
T
M
S
H
D
H
V
V
Q
F
Sea Urchin
Strong. purpuratus
XP_792466
1673
187206
L652
T
E
N
P
D
F
D
L
G
S
V
S
E
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.9
95.3
79
N.A.
85.1
23.8
N.A.
30.7
65.5
N.A.
24.2
N.A.
N.A.
N.A.
22.8
20.8
Protein Similarity:
100
44.7
96.5
82.8
N.A.
90
37.6
N.A.
44.8
75.9
N.A.
43.5
N.A.
N.A.
N.A.
38.5
30.2
P-Site Identity:
100
0
86.6
13.3
N.A.
0
0
N.A.
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
13.3
86.6
40
N.A.
26.6
20
N.A.
26.6
6.6
N.A.
26.6
N.A.
N.A.
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
19
0
19
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
10
0
10
0
0
19
0
10
10
10
10
% D
% Glu:
10
37
0
10
10
10
10
19
10
10
0
10
19
28
10
% E
% Phe:
10
0
0
0
0
19
10
0
0
19
10
0
0
0
10
% F
% Gly:
10
10
0
0
19
19
10
0
28
10
0
0
0
10
0
% G
% His:
0
0
0
10
10
0
10
10
10
0
10
10
0
0
0
% H
% Ile:
0
10
0
19
0
0
0
0
10
0
0
0
19
10
10
% I
% Lys:
0
0
0
0
10
10
0
0
0
0
0
10
10
0
10
% K
% Leu:
0
0
10
10
0
0
0
19
0
0
10
10
19
10
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% M
% Asn:
10
0
19
0
0
10
0
10
10
19
0
19
0
19
10
% N
% Pro:
0
10
10
10
0
10
10
0
0
0
10
0
0
0
0
% P
% Gln:
19
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
0
28
0
10
0
19
0
0
0
19
10
19
0
0
0
% R
% Ser:
19
0
19
10
10
0
10
37
10
10
28
10
10
0
0
% S
% Thr:
10
0
19
10
10
10
28
10
10
0
0
0
0
0
0
% T
% Val:
0
0
0
19
10
0
0
0
19
0
19
10
10
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _